Elevated serum mitochondrial DNA in females and lack of altered platelet mitochondrial methylation in patients with Parkinson´s disease

Sharma A, Schaefer ST, Sae-Lee C, Byun HM, Wüllner U

Int J Neurosci. 2020 Mar 3:1-4. doi: 10.1080/00207454.2020.1738433. 

PMID: 32125208

Platelet mitochondrial DNA methylation predicts future cardiovascular outcome in adults with overweight and obesity.

Corsi S, Iodice S, Vigna L, Cayir A, Mathers JC, Bollati V, Byun HM.

Clin Epigenetics. 2020 Feb 17;12(1):29. doi: 10.1186/s13148-020-00825-5.

PMID: 32066501

Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukaemia.

Barrow TM, Wong Doo N, Milne RL, Giles GG, Willmore E, Strathdee G, Byun HM.

Haematologica. 2020 Jan 9. pii: haematol.2019.228478. doi: 10.3324/haematol.2019.228478.

PMID: 319190931.     



Particulate matter, DNA methylation in nitric oxide synthase, and childhood respiratory disease.


Breton CV, Salam MT, Wang X, Byun HM, Siegmund KD, Gilliland FD.

Environ Health Perspect. 2012 Sep;120(9):1320-6. doi: 10.1289/ehp.1104439. Epub 2012 May 16.

PMID: 22591701 


Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells.

Shen Y, Takahashi M, Byun HM, Link A, Sharma N, Balaguer F, Leung HC, Boland CR, Goel A.

Cancer Biol Ther. 2012 May;13(7):542-52. doi: 10.4161/cbt.19604. Epub 2012 May 1.

PMID: 22415137 




Global DNA methylation and low-level exposure to benzene.

Fustinoni S, Rossella F, Polledri E, Bollati V, Campo L, Byun HM, Agnello L, Consonni D, Pesatori AC, Baccarelli A, Bertazzi PA.

Med Lav. 2012 Mar-Apr;103(2):84-95.

PMID: 22619984


Mono-allelic retrotransposon insertion addresses epigenetic transcriptional repression in human genome.

Byun HM, Heo K, Mitchell KJ, Yang AS.

J Biomed Sci. 2012 Feb 2;19:13. doi: 10.1186/1423-0127-19-13.

PMID: 22300442 


Increased mitochondrial DNA copy number in occupations associated with low-dose benzene exposure.

Carugno M, Pesatori AC, Dioni L, Hoxha M, Bollati V, Albetti B, Byun HM, Bonzini M, Fustinoni S, Cocco P, Satta G, Zucca M, Merlo DF, Cipolla M, Bertazzi PA, Baccarelli A.

Environ Health Perspect. 2012 Feb;120(2):210-5. doi: 10.1289/ehp.1103979. Epub 2011 Oct 17.

PMID: 22005026 


Genome-scale analysis of aberrant DNA methylation in colorectal cancer.

Hinoue T, Weisenberger DJ, Lange CP, Shen H, Byun HM, Van Den Berg D, Malik S, Pan F, Noushmehr H, van Dijk CM, Tollenaar RA, Laird PW.

Genome Res. 2012 Feb;22(2):271-82. doi: 10.1101/gr.117523.110. Epub 2011 Jun 9.

PMID: 21659424 


Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children.

Salam MT, Byun HM, Lurmann F, Breton CV, Wang X, Eckel SP, Gilliland FD.

J Allergy Clin Immunol. 2012 Jan;129(1):232-9.e1-7. doi: 10.1016/j.jaci.2011.09.037. Epub 2011 Nov 4.

PMID: 22055874 


Temporal stability of epigenetic markers: sequence characteristics and predictors of short-term DNA methylation variations.

Byun HM, Nordio F, Coull BA, Tarantini L, Hou L, Bonzini M, Apostoli P, Bertazzi PA, Baccarelli A.

PLoS One. 2012;7(6):e39220. doi: 10.1371/journal.pone.0039220. Epub 2012 Jun 20.

PMID: 22745719 



DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma.

Breton CV, Byun HM, Wang X, Salam MT, Siegmund K, Gilliland FD.

Am J Respir Crit Care Med. 2011 Jul 15;184(2):191-7. doi: 10.1164/rccm.201012-2029OC. Epub 2011 Apr 21.

PMID: 21512169 


Identification of preferential target sites for human DNA methyltransferases.

Choi SH, Heo K, Byun HM, An W, Lu W, Yang AS.

Nucleic Acids Res. 2011 Jan;39(1):104-18. doi: 10.1093/nar/gkq774. Epub 2010 Sep 13.

PMID: 20841325 


Increased BCR promoter DNA methylation status strongly correlates with favorable response to imatinib in chronic myeloid leukemia patients.

Koh Y, Kim DY, Park SH, Byun HM, Kim I, Yoon SS, Kim BK, Park E, Yang AS, Park S.

Oncol Lett. 2011 Jan;2(1):181-187. Epub 2010 Nov 23.

PMID: 22870150 



A phase I biological study of azacitidine (Vidaza™) to determine the optimal dose to inhibit DNA methylation.

Bernstein I, Byun HM, Mohrbacher A, Douer D, Gorospe G 3rd, Hergesheimer J, Groshen S, O'Connell C, Yang AS.

Epigenetics. 2010 Nov-Dec;5(8):750-7. doi: 10.4161/epi.5.8.13105. Epub 2010 Nov 1.

PMID: 20861661


Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.

Wolff EM, Byun HM, Han HF, Sharma S, Nichols PW, Siegmund KD, Yang AS, Jones PA, Liang G.

PLoS Genet. 2010 Apr 22;6(4):e1000917. doi: 10.1371/journal.pgen.1000917.

PMID: 20421991



Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns.

Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS.

Hum Mol Genet. 2009 Dec 15;18(24):4808-17. doi: 10.1093/hmg/ddp445. Epub 2009 Sep 23.

PMID: 19776032 


ƒ"SNPs sometimes contained in probes can interfere with methylation level detection [21]. "

Epigenomics. 2011 

Evaluation of the Infinium Methylation 450K technology.

Dedeurwaerder S1, Defrance M, Calonne E, Denis H, Sotiriou C, Fuks F.

"....as well as probes containing single-nucleotide polymorphisms (SNPs) [27]"

PLoS One. 2011

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.

Campan M1, Moffitt M, Houshdaran S, Shen H, Widschwendter M, Daxenbichler G, Long T, Marth C, Laird-Offringa IA, Press MF, Dubeau L, Siegmund KD, Wu AH, Groshen S, Chandavarkar U, Roman LD, Berchuck A, Pearce CL, Laird PW.

Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation.

Breton CV, Byun HM, Wenten M, Pan F, Yang A, Gilliland FD.

Am J Respir Crit Care Med. 2009 Sep 1;180(5):462-7. doi: 10.1164/rccm.200901-0135OC. Epub 2009 Jun 4.

PMID: 19498054

Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer.

Choi SH, Worswick S, Byun HM, Shear T, Soussa JC, Wolff EM, Douer D, Garcia-Manero G, Liang G, Yang AS.

Int J Cancer. 2009 Aug 1;125(3):723-9. doi: 10.1002/ijc.24384.

PMID: 19437537 



Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.

Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long T, Laird PW, Marquez VE, Jones PA.

Cancer Prev Res (Phila). 2008 Sep;1(4):233-40. doi: 10.1158/1940-6207.CAPR-07-0008. Epub 2008 Mar 19.

PMID: 19138966 



2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.

Byun HM, Choi SH, Laird PW, Trinh B, Siddiqui MA, Marquez VE, Yang AS.

Cancer Lett. 2008 Aug 8;266(2):238-48. doi: 10.1016/j.canlet.2008.02.069. Epub 2008 May 21.

PMID: 18499340

  • Patent

N4 modifications of pyrimidine analogs and uses thereof US 20080234223 A1, 2007



Examination of IGF2 and H19 loss of imprinting in bladder cancer.

Byun HM, Wong HL, Birnstein EA, Wolff EM, Liang G, Yang AS.

Cancer Res. 2007 Nov 15;67(22):10753-8.

PMID: 18006818 


Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.

Choi SH, Byun HM, Kwan JM, Issa JP, Yang AS.

Br J Haematol. 2007 Sep;138(5):616-23.

PMID: 17686055


Initiation site of Ca(2+) entry evoked by endoplasmic reticulum Ca(2+) depletion in mouse parotid and pancreatic acinar cells.

Jo H, Byun HM, Lee SI, Shin DM.

Yonsei Med J. 2007 Jun 30;48(3):526-30.

PMID: 17594163 


Biodistribution and tissue expression kinetics of plasmid DNA complexed with polyethylenimines of different molecular weight and structure.

Jeong GJ, Byun HM, Kim JM, Yoon H, Choi HG, Kim WK, Kim SJ, Oh YK.

J Control Release. 2007 Mar 12;118(1):118-25. Epub 2006 Dec 15.

PMID: 17250923


Changes in DNA methylation patterns in subjects exposed to low-dose benzene.

Bollati V, Baccarelli A, Hou L, Bonzini M, Fustinoni S, Cavallo D, Byun HM, Jiang J, Marinelli B, Pesatori AC, Bertazzi PA, Yang AS.

Cancer Res. 2007 Feb 1;67(3):876-80.

PMID: 17283117 


Enhanced brain targeting efficiency of intranasally administered plasmid DNA: an alternative route for brain gene therapy.

Han IK, Kim MY, Byun HM, Hwang TS, Kim JM, Hwang KW, Park TG, Jung WW, Chun T, Jeong GJ, Oh YK.

J Mol Med (Berl). 2007 Jan;85(1):75-83. Epub 2006 Nov 7.

PMID: 17089096



Rapid and quantitative method of allele-specific DNA methylation analysis.

Wong HL, Byun HM, Kwan JM, Campan M, Ingles SA, Laird PW, Yang AS.

Biotechniques. 2006 Dec;41(6):734-9.

PMID: 17191619 

...thus allowing for separate analysis of maternal and paternal alleles.[8]​

...thus allowing for separate analysis of maternal and paternal alleles.[8]


Plasmid vectors harboring cellular promoters can induce prolonged gene expression in hematopoietic and mesenchymal progenitor cells.

Byun HM, Suh D, Jeong Y, Wee HS, Kim JM, Kim WK, Ko JJ, Kim JS, Lee YB, Oh YK.

Biochem Biophys Res Commun. 2005 Jul 1;332(2):518-23.

PMID: 15893736



Erythrocyte ghost-mediated gene delivery for prolonged and blood-targeted expression.

Byun HM, Suh D, Yoon H, Kim JM, Choi HG, Kim WK, Ko JJ, Oh YK.

Gene Ther. 2004 Mar;11(5):492-6.

PMID: 14973541

  • Patent

Erythrocyte ghosts containing a desired gene for biocompatible gene systems’ Korea Patent, Registration Date; 27 December 2004



Enhanced immunogenicity of DNA fusion vaccine encoding secreted hepatitis B surface antigen and chemokine RANTES.

Kim SJ, Suh D, Park SE, Park JS, Byun HM, Lee C, Lee SY, Kim I, Oh YK.

Virology. 2003 Sep 15;314(1):84-91.

PMID: 14517062 



Cloning of ribosomal protein S6 kinase cDNA and its involvement in meiotic maturation in Rana dybowskii oocytes.

Byun HM, Kang SG, Kang HM.

Mol Cells. 2002 Aug 31;14(1):16-23.

PMID: 12243347


Exposure to environmental toxicants reduces global N6-methyladenosine RNA methylation and alters expression of RNA methylation modulator genes.

Cayir A, Barrow TM, Guo L, Byun HM.

Environ Res. 2019 May 14;175:228-234. doi: 10.1016/j.envres.2019.05.011.

PMID: 31146095

Psychosocial stress is associated with benign breast disease in young Chinese women: results from Project ELEFANT.

Barrow TM, Peng C, Wilson A, Wang H, Liu H, Shen L, Tang NJ, Sae-Lee C, Li PH, Guo L, Byun HM.

Breast Cancer Res Treat. 2019 Jan;173(1):217-224. doi: 10.1007/s10549-018-4979-4. Epub 2018 Sep 25.

PMID: 30255453


Occupational noise exposure is associated with hypertension in China: Results from project ELEFANT.

Cayir A, Barrow TM, Wang H, Liu H, Li C, Ding N, Li Y, Kang CM, Guo L, Li PH, Byun HM.

PLoS One. 2018 Dec 31;13(12):e0209041. doi: 10.1371/journal.pone.0209041. eCollection 2018.

PMID: 30596670 


Dietary Intervention Modifies DNA Methylation Age Assessed by the Epigenetic Clock.

Sae-Lee C, Corsi S, Barrow TM, Kuhnle GGC, Bollati V, Mathers JC, Byun HM.

Mol Nutr Food Res. 2018 Dec;62(23):e1800092. doi: 10.1002/mnfr.201800092. Epub 2018 Nov 2.

PMID: 30350398


Obesity as an effect modifier of the association between mensrual abnormalities and hypertension in young adult women: Results from Project ELEFANT.

Xu H, Li PH, Barrow TM, Colicino E, Li C, Song R, Liu H, Tang NJ, Liu S, Guo L, Byun HM.

PLoS One. 2018 Nov 28;13(11):e0207929. doi: 10.1371/journal.pone.0207929. eCollection 2018.

PMID: 30485368 


Age at menarche and prevention of hypertension through lifestyle in young Chinese adult women: result from project ELEFANT.

Guo L, Peng C, Xu H, Wilson A, Li PH, Wang H, Liu H, Shen L, Chen X, Qi X, Tang NJ, Barrow TM, Byun HM.

BMC Womens Health. 2018 Nov 9;18(1):182. doi: 10.1186/s12905-018-0677-y.

PMID: 30413197 


Aberrant promoter methylation in genes related to hematopoietic malignancy in workers exposed to a VOC mixture.

Jiménez-Garza O, Guo L, Byun HM, Carrieri M, Bartolucci GB, Barrón-Vivanco BS, Baccarelli AA.

Toxicol Appl Pharmacol. 2018 Jan 15;339:65-72. doi: 10.1016/j.taap.2017.12.002. Epub 2017 Dec 5.

PMID: 29217486



Promoter methylation status in genes related with inflammation, nitrosative stress and xenobiotic metabolism in low-level benzene exposure: Searching for biomarkers of oncogenesis.

Jiménez-Garza O, Guo L, Byun HM, Carrieri M, Bartolucci GB, Zhong J, Baccarelli AA.

Food Chem Toxicol. 2017 Nov;109(Pt 1):669-676. doi: 10.1016/j.fct.2017.08.019. Epub 2017 Aug 18.

PMID: 28823944


Histone 3 modifications and blood pressure in the Beijing Truck Driver Air Pollution Study.

Kresovich JK, Zhang Z, Fang F, Zheng Y, Sanchez-Guerra M, Joyce BT, Zhong J, Chervona Y, Wang S, Chang D, McCracken JP, Díaz A, Bonzini M, Carugno M, Koutrakis P, Kang CM, Bian S, Gao T, Byun HM, Schwartz J, Baccarelli AA, Hou L.

Biomarkers. 2017 Sep;22(6):584-593. doi: 10.1080/1354750X.2017.1347961. Epub 2017 Jul 26.

PMID: 28678539 


Regulating role of fetal thyroid hormones on placental mitochondrial DNA methylation: epidemiological evidence from the ENVIRONAGE birth cohort study.

Janssen BG, Byun HM, Roels HA, Gyselaers W, Penders J, Baccarelli AA, Nawrot TS.

Clin Epigenetics. 2017 Jun 21;9:66. doi: 10.1186/s13148-017-0366-y. eCollection 2017.

PMID: 28649287 


Impact of Chromosomal Rearrangement upon DNA Methylation Patterns in Leukemia.

Byun HM, Eshaghian S, Douer D, Trent J, Garcia-Manero G, Bhatia R, Siegmund K, Yang AS.

Open Med (Wars). 2017 May 4;12:76-85. doi: 10.1515/med-2017-0014. eCollection 2017.

PMID: 28730166 


Pesticide use and LINE-1 methylation among male private pesticide applicators in the Agricultural Health Study.

Alexander M, Koutros S, Bonner MR, Barry KH, Alavanja MCR, Andreotti G, Byun HM, Chen L, Beane Freeman LE, Hofmann JN, Kamel F, Moore LE, Baccarelli A, Rusiecki J.

Environ Epigenet. 2017 May 3;3(2):dvx005. doi: 10.1093/eep/dvx005. eCollection 2017 May.

PMID: 29492307 


Effects of environmental noise exposure on DNA methylation in the brain and metabolic health.

Guo L, Li PH, Li H, Colicino E, Colicino S, Wen Y, Zhang R, Feng X, Barrow TM, Cayir A, Baccarelli AA, Byun HM.

Environ Res. 2017 Feb;153:73-82. doi: 10.1016/j.envres.2016.11.017. Epub 2016 Nov 30.

PMID: 27914298


Changes in DNA Methylation in Mouse Lungs after a Single Intra-Tracheal Administration of Nanomaterials.

Tabish AM, Poels K, Byun HM, Luyts K, Baccarelli AA, Martens J, Kerkhofs S, Seys S, Hoet P, Godderis L.

PLoS One. 2017 Jan 12;12(1):e0169886. doi: 10.1371/journal.pone.0169886. eCollection 2017.

PMID: 28081255 


Placental mitochondrial DNA and CYP1A1 gene methylation as molecular signatures for tobacco smoke exposure in pregnant women and the relevance for birth weight.

Janssen BG, Gyselaers W, Byun HM, Roels HA, Cuypers A, Baccarelli AA, Nawrot TS.

J Transl Med. 2017 Jan 4;15(1):5. doi: 10.1186/s12967-016-1113-4.

PMID: 28052772 


High pesticide exposure events and DNA methylation among pesticide applicators in the agricultural health study.

Rusiecki JA, Beane Freeman LE, Bonner MR, Alexander M, Chen L, Andreotti G, Barry KH, Moore LE, Byun HM, Kamel F, Alavanja M, Hoppin JA, Baccarelli A.

Environ Mol Mutagen. 2017 Jan;58(1):19-29. doi: 10.1002/em.22067. Epub 2016 Dec 20.

PMID: 27996157 


The effect of morphine upon DNA methylation in ten regions of the rat brain.

Barrow TM, Byun HM, Li X, Smart C, Wang YX, Zhang Y, Baccarelli AA, Guo L.

Epigenetics. 2017;12(12):1038-1047. doi: 10.1080/15592294.2017.1398296. Epub 2018 Jan 22.

PMID: 29111854 


Increased methylation of repetitive elements and DNA repair genes is associated with higher DNA oxidation in children in an urbanized, industrial environment.

Alvarado-Cruz I, Sánchez-Guerra M, Hernández-Cadena L, De Vizcaya-Ruiz A, Mugica V, Pelallo-Martínez NA, Solís-Heredia MJ, Byun HM, Baccarelli A, Quintanilla-Vega B.

Mutat Res. 2017 Jan;813:27-36. doi: 10.1016/j.mrgentox.2016.11.007. Epub 2016 Nov 22.

PMID: 28010926



Particulate Air Pollution and Fasting Blood Glucose in Nondiabetic Individuals: Associations and Epigenetic Mediation in the Normative Aging Study, 2000-2011.

Peng C, Bind MC, Colicino E, Kloog I, Byun HM, Cantone L, Trevisi L, Zhong J, Brennan K, Dereix AE, Vokonas PS, Coull BA, Schwartz JD, Baccarelli AA.

Environ Health Perspect. 2016 Nov;124(11):1715-1721. Epub 2016 May 26.

PMID: 27219535 


Childhood abuse, promoter methylation of leukocyte NR3C1 and the potential modifying effect of emotional support.

Shields AE, Wise LA, Ruiz-Narvaez EA, Seddighzadeh B, Byun HM, Cozier YC, Rosenberg L, Palmer JR, Baccarelli AA.

Epigenomics. 2016 Nov;8(11):1507-1517. Epub 2016 Sep 13.

PMID: 27620456 


Childhood abuse, promoter methylation of leukocyte NR3C1 and the potential modifying effect of emotional support

Mitochondrial Epigenetics and Environmental Exposure.

Lambertini L, Byun HM.

Curr Environ Health Rep. 2016 Sep;3(3):214-24. doi: 10.1007/s40572-016-0103-2. Review.

PMID: 27344144


Effects of Air Pollution and Blood Mitochondrial DNA Methylation on Markers of Heart Rate Variability.

Byun HM, Colicino E, Trevisi L, Fan T, Christiani DC, Baccarelli AA.

J Am Heart Assoc. 2016 Apr 22;5(4). pii: e003218. doi: 10.1161/JAHA.116.003218.

PMID: 27107129 


Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory Disease.

Cahill KN, Raby BA, Zhou X, Guo F, Thibault D, Baccarelli A, Byun HM, Bhattacharyya N, Steinke JW, Boyce JA, Laidlaw TM.

Am J Respir Cell Mol Biol. 2016 Jan;54(1):34-40. doi: 10.1165/rcmb.2014-0486OC.

PMID: 26051534 



CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit.

Jiménez-Garza O, Baccarelli AA, Byun HM, Márquez-Gamiño S, Barrón-Vivanco BS, Albores A.

Toxicol Appl Pharmacol. 2015 Aug 1;286(3):207-15. doi: 10.1016/j.taap.2015.04.016. Epub 2015 May 9.

PMID: 25963742


Platelet mitochondrial DNA methylation: a potential new marker of cardiovascular disease.

Baccarelli AA, Byun HM.

Clin Epigenetics. 2015 Apr 16;7:44. doi: 10.1186/s13148-015-0078-0. eCollection 2015.

PMID: 25901189 


Epigenetic effects of low perinatal doses of flame retardant BDE-47 on mitochondrial and nuclear genes in rat offspring.

Byun HM, Benachour N, Zalko D, Frisardi MC, Colicino E, Takser L, Baccarelli AA.

Toxicology. 2015 Feb 3;328:152-9. doi: 10.1016/j.tox.2014.12.019. Epub 2014 Dec 19.

PMID: 25533936 


Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of Toll-like receptor 2 and dietary flavonoid intake.

Zhong J, Colicino E, Lin X, Mehta A, Kloog I, Zanobetti A, Byun HM, Bind MA, Cantone L, Prada D, Tarantini L, Trevisi L, Sparrow D, Vokonas P, Schwartz J, Baccarelli AA.

J Am Heart Assoc. 2015 Jan 27;4(1):e001423. doi: 10.1161/JAHA.114.001423. Erratum in: J Am Heart Assoc. 2016;5(1). pii: e002008. doi: 10.1161/JAHA.115.002008.

PMID: 25628407 


Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight.

Burris HH, Baccarelli AA, Byun HM, Cantoral A, Just AC, Pantic I, Solano-Gonzalez M, Svensson K, Tamayo y Ortiz M, Zhao Y, Wright RO, Téllez-Rojo MM.

Epigenetics. 2015;10(10):913-21. doi: 10.1080/15592294.2015.1078963. Epub 2015 Aug 7.

PMID: 26252179 


Placental mitochondrial methylation and exposure to airborne particulate matter in the early life environment: An ENVIRONAGE birth cohort study.

Janssen BG, Byun HM, Gyselaers W, Lefebvre W, Baccarelli AA, Nawrot TS.

Epigenetics. 2015;10(6):536-44. doi: 10.1080/15592294.2015.1048412.

PMID: 25996590 


Effects of particulate matter exposure on blood 5-hydroxymethylation: results from the Beijing truck driver air pollution study.

Sanchez-Guerra M, Zheng Y, Osorio-Yanez C, Zhong J, Chervona Y, Wang S, Chang D, McCracken JP, Díaz A, Bertazzi PA, Koutrakis P, Kang CM, Zhang X, Zhang W, Byun HM, Schwartz J, Hou L, Baccarelli AA.

Epigenetics. 2015;10(7):633-42. doi: 10.1080/15592294.2015.1050174.

PMID: 25970091 


Assessment of Changes in Global DNA Methylation Levels by Pyrosequencing® of Repetitive Elements.

Tabish AM, Baccarelli AA, Godderis L, Barrow TM, Hoet P, Byun HM.

Methods Mol Biol. 2015;1315:201-7. doi: 10.1007/978-1-4939-2715-9_15.

PMID: 26103901


Analysis of pollutant-induced changes in mitochondrial DNA methylation.

Byun HM, Barrow TM.

Methods Mol Biol. 2015;1265:271-83. doi: 10.1007/978-1-4939-2288-8_19.

PMID: 25634281 



Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study.

Fan T, Fang SC, Cavallari JM, Barnett IJ, Wang Z, Su L, Byun HM, Lin X, Baccarelli AA, Christiani DC.

BMC Public Health. 2014 Dec 16;14:1279. doi: 10.1186/1471-2458-14-1279.

PMID: 25512264 


Nutrients intake is associated with DNA methylation of candidate inflammatory genes in a population of obese subjects.

Bollati V, Favero C, Albetti B, Tarantini L, Moroni A, Byun HM, Motta V, Conti DM, Tirelli AS, Vigna L, Bertazzi PA, Pesatori AC.

Nutrients. 2014 Oct 22;6(10):4625-39. doi: 10.3390/nu6104625.

PMID: 25340371 


Prenatal exposure to mixtures of xenoestrogens and repetitive element DNA methylation changes in human placenta.

Vilahur N, Bustamante M, Byun HM, Fernandez MF, Santa Marina L, Basterrechea M, Ballester F, Murcia M, Tardón A, Fernández-Somoano A, Estivill X, Olea N, Sunyer J, Baccarelli AA.

Environ Int. 2014 Oct;71:81-7. doi: 10.1016/j.envint.2014.06.006. Epub 2014 Jun 28.

PMID: 24980756 


Variation of DNA methylation in candidate age-related targets on the mitochondrial-telomere axis in cord blood and placenta.

Janssen BG, Byun HM, Cox B, Gyselaers W, Izzi B, Baccarelli AA, Nawrot TS.

Placenta. 2014 Sep;35(9):665-72. doi: 10.1016/j.placenta.2014.06.371. Epub 2014 Jul 10.

PMID: 25047690 


Association between length of gestation and cervical DNA methylation of PTGER2 and LINE 1-HS.

Burris HH, Baccarelli AA, Motta V, Byun HM, Just AC, Mercado-Garcia A, Schwartz J, Svensson K, Téllez-Rojo MM, Wright RO.

Epigenetics. 2014 Aug;9(8):1083-91. doi: 10.4161/epi.29170. Epub 2014 May 14.

PMID: 24827772 


Epigenome-wide DNA methylation changes with development of arsenic-induced skin lesions in Bangladesh: a case-control follow-up study.

Seow WJ, Kile ML, Baccarelli AA, Pan WC, Byun HM, Mostofa G, Quamruzzaman Q, Rahman M, Lin X, Christiani DC.

Environ Mol Mutagen. 2014 Jul;55(6):449-56. doi: 10.1002/em.21860. Epub 2014 Feb 23.

PMID: 24677489 


Effects of short-term exposure to inhalable particulate matter on DNA methylation of tandem repeats.

Guo L, Byun HM, Zhong J, Motta V, Barupal J, Zheng Y, Dou C, Zhang F, McCracken JP, Diaz A, Marco SG, Colicino S, Schwartz J, Wang S, Hou L, Baccarelli AA.

Environ Mol Mutagen. 2014 May;55(4):322-35. doi: 10.1002/em.21838. Epub 2014 Jan 17.

PMID: 24436168 


Morphine induces redox-based changes in global DNA methylation and retrotransposon transcription by inhibition of excitatory amino acid transporter type 3-mediated cysteine uptake.

Trivedi M, Shah J, Hodgson N, Byun HM, Deth R.

Mol Pharmacol. 2014 May;85(5):747-57. doi: 10.1124/mol.114.091728. Epub 2014 Feb 25.

PMID: 24569088 


Altered methylation in tandem repeat element and elemental component levels in inhalable air particles.

Hou L, Zhang X, Zheng Y, Wang S, Dou C, Guo L, Byun HM, Motta V, McCracken J, Díaz A, Kang CM, Koutrakis P, Bertazzi PA, Li J, Schwartz J, Baccarelli AA.

Environ Mol Mutagen. 2014 Apr;55(3):256-65. doi: 10.1002/em.21829. Epub 2013 Nov 23.

PMID: 24273195 


Predicting DNA methylation level across human tissues.

Ma B, Wilker EH, Willis-Owen SA, Byun HM, Wong KC, Motta V, Baccarelli AA, Schwartz J, Cookson WO, Khabbaz K, Mittleman MA, Moffatt MF, Liang L.

Nucleic Acids Res. 2014 Apr;42(6):3515-28. doi: 10.1093/nar/gkt1380. Epub 2014 Jan 20.

PMID: 24445802 


Environmental exposure and mitochondrial epigenetics: study design and analytical challenges.

Byun HM, Baccarelli AA.

Hum Genet. 2014 Mar;133(3):247-57. doi: 10.1007/s00439-013-1417-x. Epub 2014 Jan 9. Review.

PMID: 24402053 


Single nucleotide polymorphisms on DNA methylation microarrays: precautions against confounding.

Barrow TM, Byun HM.

Epigenomics. 2014;6(6):577-9. doi: 10.2217/epi.14.55. No abstract available.

PMID: 25531251



Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutants.

Byun HM, Motta V, Panni T, Bertazzi PA, Apostoli P, Hou L, Baccarelli AA.

Part Fibre Toxicol. 2013 Jul 15;10:28. doi: 10.1186/1743-8977-10-28.

PMID: 23855992 


Storage conditions and stability of global DNA methylation in placental tissue.

Vilahur N, Baccarelli AA, Bustamante M, Agramunt S, Byun HM, Fernandez MF, Sunyer J, Estivill X.

Epigenomics. 2013 Jun;5(3):341-8. doi: 10.2217/epi.13.29.

PMID: 23750648 


Association between birth weight and DNA methylation of IGF2, glucocorticoid receptor and repetitive elements LINE-1 and Alu.

Burris HH, Braun JM, Byun HM, Tarantini L, Mercado A, Wright RJ, Schnaas L, Baccarelli AA, Wright RO, Tellez-Rojo MM.

Epigenomics. 2013 Jun;5(3):271-81. doi: 10.2217/epi.13.24.

PMID: 23750643 


Effects of airborne pollutants on mitochondrial DNA methylation.

Byun HM, Panni T, Motta V, Hou L, Nordio F, Apostoli P, Bertazzi PA, Baccarelli AA.

Part Fibre Toxicol. 2013 May 8;10:18. doi: 10.1186/1743-8977-10-18.

PMID: 23656717 

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